• Intraperitoneal This technique, which involves delivering drugs directly into the abdominal cavity, is
sometimes used for ovarian or abdominal metastatic cancer. A catheter is connected to a chamber, usually on
the chest or abdominal wall. The drugs are injected into the chamber, which releases them into the abdominal
cavity. This eliminates the need to put a new tube into the abdomen every time drugs have to be given. High
dosages can be given this way, higher than would be possible with any other method of delivery.
• Intra-arterial Drugs are often given to specific areas such as the liver, head and neck, or pelvis through the
artery supplying that area. This is usually done in the hospital, where the delivery system can continuously
infuse chemotherapy over a specific time. The drugs are given through a pump that can overcome arterial
pressure.
Which Route to Use This decision depends on several factors, mainly the type of tumor and the drug being used. There are many questions to answer. Can the drug be absorbed in the stomach? How big a dose is required? What are the side effects? Are they tolerable?
Ultimately, the decision will be made on the basis of what is the most effective way to get the highest dosage of the right drug to the right place. Whichever route is chosen, your doctor will give you and your family or friends complete information on the usual effects of the drug, its side effects, any safety precautions to take and what reactions to report.
